TY  - JOUR
AU  - Scotece, Morena
AU  - Vaamonde-García, Carlos
AU  - Lechuga-Vieco, Ana Victoria
AU  - Cortés, Alberto Centeno
AU  - Jimenez-Gomez, Maria Concepcion
AU  - Filgueira-Fernández, Purificación
AU  - Rego-Pérez, Ignacio
AU  - Enriquez, Jose Antonio
AU  - Blanco, Francisco J
PY  - 2022
DO  - 10.18632/aging.204153
UR  - http://hdl.handle.net/20.500.12105/16696
AB  - Mitochondria and mtDNA variations contribute to specific aspects of the aging process. Here, we aimed to investigate the influence of mtDNA variation on joint damage in a model of aging using conplastic mice. A conplastic (BL/6NZB) mouse strain was...
LA  - eng
PB  - Impact Journals
KW  - DNA, Mitochondrial
KW  - Osteoarthritis
KW  - 8-Hydroxy-2'-Deoxyguanosine
KW  - Aging
KW  - Animals
KW  - Beclin-1
KW  - Caspase 3
KW  - Disease Models, Animal
KW  - Ki-67 Antigen
KW  - Matrix Metalloproteinase 13
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mitochondria
KW  - beta-Galactosidase
TI  - mtDNA variability determines spontaneous joint aging damage in a conplastic mouse model.
TY  - journal article
ER  -