TY  - JOUR
AU  - van Rhijn, Norman
AU  - Hemmings, Sam
AU  - Storer, Isabelle S R
AU  - Valero, Clara
AU  - Bin Shuraym, Hajer
AU  - Goldman, Gustavo H
AU  - Gsaller, Fabio
AU  - Amich, Jorge
AU  - Bromley, Michael J
PY  - 2022
DO  - 10.1128/mbio.02215-22
UR  - http://hdl.handle.net/20.500.12105/16004
AB  - Aspergillosis, in its various manifestations, is a major cause of morbidity and mortality. Very few classes of antifungal drugs have been approved for clinical use to treat these diseases and resistance to the first-line therapeutic class, the...
LA  - eng
PB  - American Society for Microbiology (ASM)
KW  - Aspergillus fumigatus
KW  - Antagonism
KW  - Antifungal
KW  - Antimicrobial resistance
KW  - Aspergillosis
KW  - Metabolic rewiring
KW  - Metabolism
KW  - Olorofim
KW  - Orotomide
KW  - Transcription factor
KW  - Aspergillus fumigatus
KW  - Aspergillosis
KW  - Humans
KW  - Azoles
KW  - Antifungal Agents
KW  - Gene Regulatory Networks
KW  - Pyrimidines
KW  - Triazoles
KW  - Transcription Factors
KW  - Ergosterol
KW  - Drug Resistance, Fungal
KW  - Microbial Sensitivity Tests
KW  - Fungal Proteins
TI  - Antagonism of the Azoles to Olorofim and Cross-Resistance Are Governed by Linked Transcriptional Networks in Aspergillus fumigatus
TY  - journal article
ER  -