TY - GEN AU - Rubio, Leticia AU - Vargas, Antonio AU - Rivera, Patricia AU - López-Gambero, Antonio J. AU - Tovar, Rubén AU - Christians, Julian K. AU - Martín-de-las-Heras, Stella AU - Rodríguez de Fonseca, Fernando AU - Chowen, Julie A. AU - Argente, Jesús AU - Suárez, Juan PY - 2021 DO - 10.3390/ijms22084048 UR - http://hdl.handle.net/20.500.12105/18310 AB - Deficiency of pregnancy-associated plasma protein-A2 (PAPP-A2), an IGF-1 availability regulator, causes postnatal growth failure and dysregulation of bone size and density. The present study aimed to determine the effects of recombinant murine IGF-1... LA - eng PB - Multidisciplinary Digital Publishing Institute (MDPI) KW - Apatite KW - Bone KW - Collagen KW - Growth KW - IGFBP KW - Pappalysin KW - Sex difference KW - Pappa2 deficiency KW - Apatita KW - Hueso KW - Colágeno KW - Crecimiento KW - Proteínas de unión a factor de crecimiento similar a la insulina KW - Proteína plasmática asociada al embarazo KW - Características sexuales KW - Animals KW - Bone Density KW - Bone Remodeling KW - Bone Remodeling KW - Carrier Proteins KW - Collagen Type I KW - Gene Expression Regulation, Developmental KW - Humans KW - Insulin-Like Growth Factor Binding Protein 3 KW - Insulin-Like Growth Factor I KW - Mice KW - Mice, Knockout KW - Osteocalcin KW - Osteogenesis KW - Osteopontin KW - Pregnancy-Associated Plasma Protein-A KW - Sex Characteristics TI - Recombinant IGF-1 Induces Sex-Specific Changes in Bone Composition and Remodeling in Adult Mice with Pappa2 Deficiency TY - research article ER -