TY - GEN AU - Portela, Marta AU - Segura-Collar, Berta AU - Argudo, Irene AU - Sáiz, Almudena AU - Gargini, Ricardo AU - Sánchez-Gómez, Pilar AU - Casas-Tinto, Sergio PY - 2019 DO - 10.1002/glia.23551 UR - http://hdl.handle.net/20.500.12105/10787 AB - Genetic lesions in glioblastoma (GB) include constitutive activation of PI3K and EGFR pathways to drive cellular proliferation and tumor malignancy. An RNAi genetic screen, performed in Drosophila melanogaster to discover new modulators of GB... LA - eng PB - Wiley KW - Animals KW - Animals, Genetically Modified KW - Brain KW - Brain Neoplasms KW - Cell Line, Tumor KW - Disease Models, Animal KW - Drosophila Proteins KW - Drosophila melanogaster KW - Enzyme Inhibitors KW - ErbB Receptors KW - Female KW - Gene Expression Regulation, Neoplastic KW - Glioma KW - Heterografts KW - Humans KW - Leupeptins KW - Luminescent Proteins KW - Male KW - Mice KW - Protein Transport KW - RNA Interference TI - Oncogenic dependence of glioma cells on kish/TMEM167A regulation of vesicular trafficking TY - preprint ER -