TY  - JOUR
AU  - Leandro-García, Luis J
AU  - Leskelä, Susanna
AU  - Jara, Carlos
AU  - Gréen, Henrik
AU  - Avall-Lundqvist, Elisabeth
AU  - Wheeler, Heather E
AU  - Dolan, M Eileen
AU  - Inglada-Perez, Lucia
AU  - Maliszewska, Agnieszka
AU  - de Cubas, Aguirre A
AU  - Comino-Méndez, Iñaki
AU  - Mancikova, Veronika
AU  - Cascón, Alberto
AU  - Rodríguez-Antona, Cristina
AU  - Robledo Batanero, Mercedes
PY  - 2012
DO  - 10.1158/1078-0432.CCR-12-1221
UR  - http://hdl.handle.net/20.500.12105/17498
AB  - PURPOSEPeripheral neuropathy is the dose-limiting toxicity of paclitaxel, a chemotherapeutic drug widely used to treat several solid tumors such as breast, lung, and ovary. The cytotoxic effect of paclitaxel is mediated through β-tubulin binding in...
LA  - eng
PB  - American Association for Cancer Research (AACR)
KW  - Polymorphism, Genetic
KW  - Adult
KW  - Aged
TI  - Regulatory polymorphisms in β-tubulin IIa are associated with paclitaxel-induced peripheral neuropathy.
TY  - journal article
ER  -