TY - JOUR AU - Gonzalez-Granado, Jose Maria AU - Silvestre-Roig, Carlos AU - Rocha-Perugini, Vera AU - Trigueros-Motos, Laia AU - Cibrian, Danay AU - Morlino, Giulia AU - Blanco-Berrocal, Marta AU - Osorio, Fernando Garcia AU - Freije, José María Pérez AU - López-Otín, Carlos AU - Sanchez-Madrid, Francisco AU - Andres, Vicente PY - 2014 DO - 10.1126/scisignal.2004872 SN - 1945-0877 UR - http://hdl.handle.net/20.500.12105/7919 AB - In many cell types, nuclear A-type lamins regulate multiple cellular functions, including higher-order genome organization, DNA replication and repair, gene transcription, and signal transduction; however, their role in specialized immune cells... LA - eng PB - American Association for the Advancement of Science (AAAS) KW - Actin Cytoskeleton KW - Actins KW - Animals KW - Humans KW - Immunological Synapses KW - Jurkat Cells KW - Lamin Type A KW - Lymphocyte Activation KW - MAP Kinase Signaling System KW - Mice KW - Mice, Knockout KW - Mitogen-Activated Protein Kinase 1 KW - Mitogen-Activated Protein Kinase 3 KW - Receptors, Antigen, T-Cell KW - T-Lymphocytes TI - Nuclear envelope lamin-A couples actin dynamics with immunological synapse architecture and T cell activation TY - journal article ER -