TY - JOUR AU - Oeste, Clara L AU - Díez-Dacal, Beatriz AU - Bray, Francesca AU - García de Lacoba, Mario AU - de la Torre, Beatriz G AU - Andreu, David AU - Ruiz-Sánchez, Antonio J AU - Pérez-Inestrosa, Ezequiel AU - Garcia-Dominguez, Carlota A AU - Rojas-Cabañeros, Jose Maria AU - Pérez-Sala, Dolores PY - 2011 DO - 10.1371/journal.pone.0015866 SN - 1932-6203 UR - http://hdl.handle.net/20.500.12105/7000 AB - Ras proteins are crucial players in differentiation and oncogenesis and constitute important drug targets. The localization and activity of Ras proteins are highly dependent on posttranslational modifications at their C-termini. In addition to an... LA - eng PB - Public Library of Science (PLOS) KW - Animals KW - Arsenicals KW - Binding Sites KW - Bridged Bicyclo Compounds KW - Cell Line KW - Cross-Linking Reagents KW - Cyclopentanes KW - Cysteine KW - Enzyme Inhibitors KW - Humans KW - Prostaglandins KW - Protein Binding KW - Protein Processing, Post-Translational KW - Proto-Oncogene Proteins p21(ras) KW - Signal Transduction KW - Transfection KW - ras Proteins TI - The C-terminus of H-Ras as a target for the covalent binding of reactive compounds modulating Ras-dependent pathways TY - journal article ER -