TY  - GEN
AU  - Ye, Hui
AU  - Chen, Chaobo
AU  - Wu, Hanghang
AU  - Zheng, Kang
AU  - Martín-Adrados, Beatriz
AU  - Caparrós, Esther
AU  - Francés, Rubén
AU  - Nelson, Leonard J
AU  - Gómez Del Moral, Manuel
AU  - Asensio, Iris
AU  - Vaquero, Javier
AU  - Bañares, Rafael
AU  - Ávila, Matías A
AU  - Andrade, Raúl J
AU  - Isabel Lucena, M
AU  - Martínez-Chantar, Maria Luz
AU  - Reeves, Helen L
AU  - Masson, Steven
AU  - Blumberg, Richard S
AU  - Gracia-Sancho, Jordi
AU  - Nevzorova, Yulia A
AU  - Martínez-Naves, Eduardo
AU  - Cubero, Francisco Javier
PY  - 2022
DO  - 10.1038/s41419-022-04580-8
UR  - http://hdl.handle.net/20.500.12105/18603
AB  - Acetaminophen (APAP) hepatotoxicity induces endoplasmic reticulum (ER) stress which triggers the unfolded protein response (UPR) in hepatocytes. However, the mechanisms underlying ER stress remain poorly understood, thus reducing the options for...
LA  - eng
KW  - Acetaminophen
KW  - Animals
KW  - Autophagy
TI  - Genetic and pharmacological inhibition of XBP1 protects against APAP hepatotoxicity through the activation of autophagy.
TY  - research article
ER  -