TY - GEN AU - Baglietto-Vargas, David AU - Forner, Stefania AU - Cai, Lena AU - Martini, Alessandra C. AU - Trujillo-Estrada, Laura AU - Swarup, Vivek AU - Nguyen, Marie Minh Thu AU - Do Huynh, Kelly AU - Javonillo, Dominic I. AU - Tran, Kristine Minh AU - Phan, Jimmy AU - Jiang, Shan AU - Kramár, Enikö A. AU - Nuñez-Diaz, Cristina AU - Balderrama-Gutierrez, Gabriela AU - Garcia, Franklin AU - Childs, Jessica AU - Rodriguez-Ortiz, Carlos J. AU - Garcia-Leon, Juan Antonio AU - Kitazawa, Masashi AU - Shahnawaz, Mohammad AU - Matheos, Dina P. AU - Ma, Xinyi AU - Da Cunha, Celia AU - Walls, Ken C. AU - Ager, Rahasson R. AU - Soto, Claudio AU - Gutierrez, Antonia AU - Moreno-Gonzalez, Ines AU - Mortazavi, Ali AU - Tenner, Andrea J. AU - MacGregor, Grant R. AU - Wood, Marcelo AU - Green, Kim N. AU - LaFerla, Frank M. PY - 2021 DO - 10.1038/s41467-021-22624-z UR - http://hdl.handle.net/20.500.12105/18320 AB - The majority of Alzheimer's disease (AD) cases are late-onset and occur sporadically, however most mouse models of the disease harbor pathogenic mutations, rendering them better representations of familial autosomal-dominant forms of the disease.... LA - eng PB - Springer KW - Periodic acid-schiff KW - Exon KW - Cognition KW - Mutation KW - Gene expression KW - Alzheimer disease KW - Reacción del ácido peryódico de Schiff KW - Exones KW - Cognición KW - Mutación KW - Expresión génica KW - Enfermedad de Alzheimer KW - Alzheimer Disease KW - Amyloid beta-Peptides KW - Amyloid beta-Protein Precursor KW - Animals KW - Brain KW - Female KW - Gene Expression Profiling KW - Gene Ontology KW - Gene Regulatory Networks KW - Humans KW - Male KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Neuronal Plasticity KW - Disease Models, Animal KW - Mutation KW - Mice KW - Periodic Acid KW - Amino Acids KW - Mobile Applications KW - Exons KW - Cognition KW - Gene Expression TI - Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology TY - research article ER -