TY - GEN AU - Decara, Juan M AU - Vázquez-Villa, Henar AU - Brea, José AU - Alonso, Mónica AU - Srivastava, Raj Kamal AU - Orio, Laura AU - Alén, Francisco AU - Suárez, Juan AU - Baixeras, Elena AU - García-Cárceles, Javier AU - Escobar-Peña, Andrea AU - Lutz, Beat AU - Rodríguez, Ramón AU - Codesido, Eva AU - Garcia-Ladona, F Javier AU - Bennett, Teresa A AU - Ballesteros, Juan A AU - Cruces, Jacobo AU - Loza, María I AU - Benhamú, Bellinda AU - Rodríguez de Fonseca, Fernando AU - López-Rodríguez, María L PY - 2022 DO - 10.1021/acs.jmedchem.1c01842 UR - http://hdl.handle.net/20.500.12105/18796 AB - Peptidic agonists of the glucagon-like peptide-1 receptor (GLP-1R) have gained a prominent role in the therapy of type-2 diabetes and are being considered for reducing food intake in obesity. Potential advantages of small molecules acting as positive... LA - eng KW - Administration, Oral KW - Animals KW - Diabetes Mellitus, Type 2 KW - Glucagon-Like Peptide-1 Receptor KW - Obesity KW - Peptides TI - Discovery of V-0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor toward Oral Treatment for "Diabesity". TY - research article ER -