TY  - JOUR
AU  - Fuster, José J
AU  - MacLauchlan, Susan
AU  - Zuriaga, María A
AU  - Polackal, Maya N
AU  - Ostriker, Allison C
AU  - Chakraborty, Raja
AU  - Wu, Chia-Ling
AU  - Sano, Soichi
AU  - Muralidharan, Sujatha
AU  - Rius, Cristina
AU  - Vuong, Jacqueline
AU  - Jacob, Sophia
AU  - Muralidhar, Varsha
AU  - Robertson, Avril A B
AU  - Cooper, Matthew A
AU  - Andres, Vicente
AU  - Hirschi, Karen K
AU  - Martin, Kathleen A
AU  - Walsh, Kenneth
PY  - 2017
DO  - 10.1126/science.aag1381
SN  - 0036-8075
UR  - http://hdl.handle.net/20.500.12105/9683
AB  - Human aging is associated with an increased frequency of somatic mutations in hematopoietic cells. Several of these recurrent mutations, including those in the gene encoding the epigenetic modifier enzyme TET2, promote expansion of the mutant blood...
LA  - eng
PB  - American Association for the Advancement of Science (AAAS)
KW  - Animals
KW  - Atherosclerosis
KW  - DNA-Binding Proteins
KW  - Hematopoiesis
KW  - Hematopoietic Stem Cells
KW  - Inflammasomes
KW  - Macrophages
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mutation
KW  - NLR Family, Pyrin Domain-Containing 3 Protein
KW  - Plaque, Atherosclerotic
KW  - Proto-Oncogene Proteins
KW  - Receptors, LDL
TI  - Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice
TY  - journal article
ER  -