TY - JOUR AU - Varela, Elisa AU - Muñoz-Lorente, Miguel A AU - Tejera, Agueda AU - Ortega Jimenez, Sagrario AU - Blasco , MA PY - 2016 DO - 10.1038/ncomms11739 SN - 2041-1723 UR - http://hdl.handle.net/20.500.12105/7868 AB - Although telomere length is genetically determined, mouse embryonic stem (ES) cells with telomeres of twice the normal size have been generated. Here, we use such ES cells with 'hyper-long' telomeres, which also express green fluorescent protein... LA - eng PB - Nature Publishing Group KW - Aging KW - Animals KW - Brain KW - DNA Damage KW - Embryonic Stem Cells KW - Female KW - Gene Expression KW - Genes, Reporter KW - Green Fluorescent Proteins KW - Intestinal Mucosa KW - Intestines KW - Longevity KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Primary Cell Culture KW - Skin KW - Surgical Wound KW - Telomere KW - Telomere Shortening KW - Wound Healing KW - Telomere Homeostasis TI - Generation of mice with longer and better preserved telomeres in the absence of genetic manipulations TY - journal article ER -