TY  - JOUR
AU  - Quinones, Mar
AU  - Al-Massadi, Omar
AU  - Folgueira, Cintia
AU  - Bremser, Stephan
AU  - Gallego, Rosalia
AU  - Torres-Leal, Leonardo
AU  - Haddad-Tovolli, Roberta
AU  - Garcia-Caceres, Cristina
AU  - Hernandez-Bautista, Rene
AU  - Lam, Brian Y. H.
AU  - Beiroa, Daniel
AU  - Sanchez-Rebordelo, Estrella
AU  - Senra, Ana
AU  - Malagon, Jose A.
AU  - Valerio, Patricia
AU  - Fondevila, Marcos F.
AU  - Ferno, Johan
AU  - Malagon, Maria M.
AU  - Contreras, Raian
AU  - Pfluger, Paul
AU  - Bruening, Jens C.
AU  - Yeo, Giles
AU  - Tschoep, Matthias
AU  - Dieguez, Carlos
AU  - Lopez, Miguel
AU  - Claret, Marc
AU  - Kloppenburg, Peter
AU  - Sabio, Guadalupe
AU  - Nogueiras, Ruben
PY  - 2018
DO  - 10.1038/s41467-018-05711-6
SN  - 2041-1723
UR  - http://hdl.handle.net/20.500.12105/6536
AB  - p53 is a well-known tumor suppressor that has emerged as an important player in energy balance. However, its metabolic role in the hypothalamus remains unknown. Herein, we show that mice lacking p53 in agouti-related peptide (AgRP), but not...
LA  - eng
PB  - Nature Publishing Group
KW  - AGOUTI-RELATED PEPTIDE
KW  - ADIPOSE-TISSUE THERMOGENESIS
KW  - REGULATES FOOD-INTAKE
KW  - CONNECTS ER STRESS
KW  - ENERGY-BALANCE
KW  - ENDOPLASMIC-RETICULUM
KW  - HYPOTHALAMIC AMPK
KW  - GLUCOSE-HOMEOSTASIS
KW  - POMC NEURONS
KW  - METABOLIC-REGULATION
TI  - p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1
TY  - journal article
ER  -