TY  - JOUR
AU  - Willis, B. Cicero
AU  - Pandit, Sandeep V.
AU  - Ponce-Balbuena, Daniela
AU  - Zarzoso, Manuel
AU  - Guerrero-Serna, Guadalupe
AU  - Limbu, Bijay
AU  - Deo, Makarand
AU  - Camors, Emmanuel
AU  - Ramirez, Rafael J.
AU  - Mironov, Sergey
AU  - Herron, Todd J.
AU  - Valdivia, Hector H.
AU  - Jalife, Jose
PY  - 2016
DO  - 10.1161/CIRCULATIONAHA.116.021936
SN  - 0009-7322
UR  - http://hdl.handle.net/20.500.12105/5219
AB  - Background-In catecholaminergic polymorphic ventricular tachycardia (CPVT), cardiac Purkinje cells (PCs) appear more susceptible to Ca2+ dysfunction than ventricular myocytes (VMs). The underlying mechanisms remain unknown. Using a CPVT mouse...
LA  - eng
PB  - Lippincott Williams & Wilkins (LWW)
KW  - Arrhythmias, cardiac
KW  - Calcium
KW  - Calcium signaling
KW  - Sodium-calcium exchanger
KW  - BETA-ADRENERGIC STIMULATION
KW  - CARDIAC RYANODINE RECEPTOR
KW  - IN MOUSE MODEL
KW  - SUDDEN-DEATH
KW  - CELLULAR MECHANISM
KW  - CA2+ ACTIVATION
KW  - MURINE HEART
KW  - FIBERS
KW  - CONTRACTION
KW  - MYOCARDIUM
TI  - Constitutive Intracellular Na+ Excess in Purkinje Cells Promotes Arrhythmogenesis at Lower Levels of Stress Than Ventricular Myocytes From Mice With Catecholaminergic Polymorphic Ventricular Tachycardia
TY  - journal article
ER  -