TY  - JOUR
AU  - Diaz-Guerra, Teresa M.
AU  - Mellado, Emilia
AU  - Cuenca-Estrella, Manuel
AU  - Rodriguez-Tudela, Juan Luis
PY  - 2003
DO  - 10.1128/aac.47.3.1120-1124.2003
SN  - 0066-4804
UR  - http://hdl.handle.net/20.500.12105/8234
AB  - The genes encoding 14alpha-sterol demethylases (cyp51A and cyp51B) were analyzed in 12 itraconazole (ITC)-resistant and three ITC-susceptible clinical isolates of Aspergillus fumigatus. Six ITC-resistant strains exhibited a substitution of another...
LA  - eng
PB  - American Society for Microbiology (ASM)
KW  - Amino Acid Substitution
KW  - Antifungal Agents
KW  - Aspergillus fumigatus
KW  - Base Sequence
KW  - Cytochrome P-450 Enzyme System
KW  - Drug Resistance, Fungal
KW  - Electroporation
KW  - Fungal Proteins
KW  - Itraconazole
KW  - Microbial Sensitivity Tests
KW  - Molecular Sequence Data
KW  - Point Mutation
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Transformation, Genetic
TI  - A point mutation in the 14alpha-sterol demethylase gene cyp51A contributes to itraconazole resistance in Aspergillus fumigatus
TY  - journal article
ER  -