TY  - JOUR
AU  - Cerezo-Wallis, Daniela
AU  - Contreras-Alcalde, Marta
AU  - Troulé, Kevin
AU  - Catena, Xavier
AU  - Mucientes, Cynthia
AU  - Calvo, Tonantzin G
AU  - Cañón, Estela
AU  - Tejedo, Cristina
AU  - Pennacchi, Paula C
AU  - Hogan, Sabrina
AU  - Kölblinger, Peter
AU  - Tejero, Héctor
AU  - Chen, Andrew X
AU  - Ibarz, Nuria
AU  - Graña-Castro, Osvaldo
AU  - Martinez Garcia, Maria Dolores
AU  - Muñoz, Javier
AU  - Ortiz-Romero, Pablo
AU  - Rodriguez-Peralto, José L
AU  - Gómez-López, Gonzalo
AU  - Al-Shahrour, Fatima
AU  - Rabadán, Raúl
AU  - Levesque, Mitchell P
AU  - Olmeda, David
AU  - Soengas, MS
PY  - 2020
DO  - 10.1038/s41591-020-1073-3
UR  - http://hdl.handle.net/20.500.12105/17424
AB  - An open question in aggressive cancers such as melanoma is how malignant cells can shift the immune system to pro-tumorigenic functions. Here we identify midkine (MDK) as a melanoma-secreted driver of an inflamed, but immune evasive, microenvironment...
LA  - eng
PB  - Nature Publishing Group
KW  - Animals
KW  - B7-H1 Antigen
KW  - CD8-Positive T-Lymphocytes
KW  - Carcinogenesis
KW  - Gene Expression Regulation, Neoplastic
KW  - Genetic Therapy
KW  - Humans
KW  - Melanoma, Experimental
KW  - Mice
KW  - Midkine
KW  - NF-kappa B
KW  - Programmed Cell Death 1 Receptor
KW  - Recombinant Proteins
KW  - Transcriptome
KW  - Tumor Microenvironment
TI  - Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state.
TY  - journal article
ER  -