TY - GEN AU - Tumpara, Srinu AU - Liu, Bin AU - Korenbaum, Elena AU - Jonigk, Danny AU - Jugert, Frank AU - Welte, Tobias AU - Janciauskiene, Sabina AU - Martinez-Delgado, Beatriz AU - Gomez-Mariano, Gema Maria AU - DeLuca, David S AU - Wurm, Florian M AU - Wurm, Maria J PY - 2020 DO - 10.3389/fphar.2020.00983 SN - 1663-9812 UR - http://hdl.handle.net/20.500.12105/11022 AB - Human α1-antitrypsin (AAT) is an abundant acute phase glycoprotein expressing anti-protease and immunomodulatory activities, and is used as a biopharmaceutical to treat patients with inherited AAT deficiency. The pleiotropic properties of AAT provide... LA - eng PB - Frontiers Media KW - RNA-Seq-RNA sequencing KW - Inflammation Immunomodulation KW - alpha1-antitrypin KW - Epidermis KW - topical-Skin cream TI - The Delivery of α1-Antitrypsin Therapy Through Transepidermal Route: Worthwhile to Explore TY - research article ER -