TY - GEN AU - Gallego, Alejandro AU - Mendiola, Marta AU - Hernando, Barbara AU - Berjon, Alberto AU - Cadiz, Alice AU - Chaves-Urbano, Blas AU - Heredia-Soto, Victoria AU - Spagnolo, Emanuela AU - Hernández Gutiérrez, Alicia AU - Hardisson, David AU - Macintyre, Geoff AU - Redondo, Andres AU - Garcia, Maria Jose PY - 2022 UR - https://hdl.handle.net/20.500.12105/26528 AB - Cancer-related systemic inflammation has been associated with prognosis in multiple cancer types. Conversely, local inflammation, which is characterized by dense intratumoral immune infiltrates, is a favorable predictor of survival outcome. However,... AB - This retrospective study included 119 patients (63 endometrioid and 56 clear cell ovarian carcinomas). We performed a comprehensive survival association analysis of both systemic (neutrophil-to-lymphocyte ratio or presence of endometriosis) and local... AB - Medium to high levels of intraepithelial CD8+ tumor infiltrating lymphocytes are associated with longer survival in endometrioid ovarian cancer (p=0.04). In addition, we found that intraepithelial CD8+ tumor infiltrating lymphocytes are prognostic in... AB - In this study, patients with endometrioid and clear cell ovarian cancer with moderate to high CD8+ and CD3+ intraepithelial tumor infiltrating lymphocytes had longer overall survival. Higher expression of intratumoral CD3+ and CD8+ tumor infiltrating... LA - eng PB - Elsevier KW - ovarian cancer TI - Prognostic markers of inflammation in endometrioid and clear cell ovarian cancer. TY - research article ER -