TY - JOUR AU - Hruschka, Natascha AU - Kalisz, Mark AU - Subijana, Maria AU - Graña-Castro, Osvaldo AU - Del Cano-Ochoa, Francisco AU - Brunet, Laia Paré AU - Chernukhin, Igor AU - Sagrera, Ana AU - De Reynies, Aurelien AU - Kloesch, Bernhard AU - Chin, Suet-Feung AU - Burgués, Octavio AU - Andreu, David AU - Bermejo, Begoña AU - Cejalvo, Juan Miguel AU - Sutton, Joe AU - Caldas, Carlos AU - Ramón-Maiques, Santiago AU - Carroll, Jason S AU - Prat, Aleix AU - Real Arribas, Francisco AU - Martinelli, Paola PY - 2020 DO - 10.1038/s41388-020-1376-3 UR - http://hdl.handle.net/20.500.12105/18189 AB - As the catalog of oncogenic driver mutations is expanding, it becomes clear that alterations in a given gene might have different functions and should not be lumped into one class. The transcription factor GATA3 is a paradigm of this. We investigated... LA - eng PB - Springer KW - Breast Neoplasms KW - Cell Cycle KW - Female KW - GATA3 Transcription Factor KW - Humans KW - Mutation KW - Oncogenes KW - RNA Splicing KW - RNA, Messenger KW - Receptors, Estrogen KW - Receptors, Progesterone KW - T-Lymphocytes TI - The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver. TY - journal article ER -