TY  - JOUR
AU  - Garcia-Ortiz, Almudena
AU  - Martin-Cofreces, Noa B.
AU  - Ibiza, Sales
AU  - Ortega, Angel
AU  - Izquierdo-Alvarez, Alicia
AU  - Trullo, Antonio
AU  - Victor, Victor Manuel
AU  - Calvo, Enrique
AU  - Sot, Begona
AU  - Martinez-Ruiz, Antonio
AU  - Vazquez, Jesus
AU  - Sanchez-Madrid, Francisco
AU  - Serrador, Juan M.
PY  - 2017
DO  - 10.1371/journal.pbio.2000653
SN  - 1545-7885
UR  - http://hdl.handle.net/20.500.12105/5124
AB  - The actin cytoskeleton coordinates the organization of signaling microclusters at the immune synapse (IS); however, the mechanisms involved remain poorly understood. We show here that nitric oxide (NO) generated by endothelial nitric oxide synthase...
LA  - eng
PB  - Public Library of Science (PLOS)
KW  - NITRIC-OXIDE SYNTHASE
KW  - T-CELL-ACTIVATION
KW  - IMMUNOLOGICAL SYNAPSE
KW  - RETROGRADE FLOW
KW  - ARP2/3 COMPLEX
KW  - PROTEIN
KW  - RECEPTOR
KW  - POLYMERIZATION
KW  - POLARIZATION
KW  - CYTOSKELETON
TI  - eNOS S-nitrosylates beta-actin on Cys374 and regulates PKC-theta at the immune synapse by impairing actin binding to profilin-1
TY  - journal article
ER  -