TY  - JOUR
AU  - Calvo, Patricia A
AU  - Martínez-Jiménez, María I
AU  - Díaz, Marcos
AU  - Stojkovic, Gorazd
AU  - Kasho, Kazutoshi
AU  - Guerra, Susana
AU  - Wanrooij, Sjoerd
AU  - Blanco, Luis
AU  - Mendez, Juan
PY  - 2021
DO  - 10.1093/nar/gkab634
UR  - http://hdl.handle.net/20.500.12105/13718
AB  - PrimPol is the second primase in human cells, the first with the ability to start DNA chains with dNTPs. PrimPol contributes to DNA damage tolerance by restarting DNA synthesis beyond stalling lesions, acting as a TLS primase. Multiple alignment of...
LA  - eng
PB  - Oxford University Press
KW  - DNA-POLYMERASE-GAMMA
KW  - PRIMASE
KW  - DOMAIN
KW  - ARCHITECTURE
KW  - INSIGHTS
KW  - REVEALS
KW  - RNA
KW  - Amino Acid Motifs
KW  - DNA
KW  - DNA Damage
KW  - DNA Primase
KW  - DNA Replication
KW  - DNA-Directed DNA Polymerase
KW  - Humans
KW  - Multifunctional Enzymes
KW  - RNA-Binding Protein FUS
TI  - Motif WFYY of human PrimPol is crucial to stabilize the incoming 3'-nucleotide during replication fork restart.
TY  - journal article
ER  -