TY - JOUR AU - Johnen, Heiko AU - González-Silva, Laura AU - Carramolino, Laura AU - Flores, Juana Maria AU - Torres, Miguel AU - Salvador, Jesús M PY - 2013 DO - 10.1371/journal.pone.0058751 SN - 1932-6203 UR - http://hdl.handle.net/20.500.12105/7581 AB - In humans and most mammals, differentiation of the embryonic gonad into ovaries or testes is controlled by the Y-linked gene SRY. Here we show a role for the Gadd45g protein in this primary sex differentiation. We characterized mice deficient in... LA - eng PB - Public Library of Science (PLOS) KW - Animals KW - Cell Differentiation KW - Female KW - Gene Expression Regulation, Developmental KW - Gonadal Dysgenesis, 46,XY KW - Humans TI - Gadd45g is essential for primary sex determination, male fertility and testis development TY - journal article ER -