TY - JOUR AU - Bertuzzi, Margherita AU - Schrettl, Markus AU - Alcazar-Fuoli, Laura AU - Cairns, Timothy C AU - Muñoz, Alberto AU - Walker, Louise A AU - Herbst, Susanne AU - Safari, Maryam AU - Cheverton, Angela M AU - Chen, Dan AU - Liu, Hong AU - Saijo, Shinobu AU - Fedorova, Natalie D AU - Armstrong-James, Darius AU - Munro, Carol A AU - Read, Nick D AU - Filler, Scott G AU - Espeso, Eduardo A AU - Nierman, William C AU - Haas, Hubertus AU - Bignell, Elaine M PY - 2014 DO - 10.1371/journal.ppat.1004413 SN - 1553-7374 UR - http://hdl.handle.net/20.500.12105/6837 AB - Destruction of the pulmonary epithelium is a major feature of lung diseases caused by the mould pathogen Aspergillus fumigatus. Although it is widely postulated that tissue invasion is governed by fungal proteases, A. fumigatus mutants lacking... LA - eng PB - Public Library of Science (PLOS) KW - Animals KW - Aspergillus fumigatus KW - Epithelial Cells KW - Fungal Proteins KW - Hydrogen-Ion Concentration KW - Mice KW - Pulmonary Aspergillosis KW - Transcription Factors TI - The pH-responsive PacC transcription factor of Aspergillus fumigatus governs epithelial entry and tissue invasion during pulmonary aspergillosis TY - journal article ER -