TY  - JOUR
AU  - Mata-Garrido, Jorge
AU  - Tapia, Olga
AU  - Casafont, Iñigo
AU  - Berciano, Maria T
AU  - Cuadrado Garcia, Ana
AU  - Lafarga, Miguel
PY  - 2018
DO  - 10.1186/s40478-018-0573-6
SN  - 2051-5960
UR  - http://hdl.handle.net/20.500.12105/6609
AB  - Neurons are highly vulnerable to DNA damage induced by genotoxic agents such as topoisomerase activity, oxidative stress, ionizing radiation (IR) and chemotherapeutic drugs. To avert the detrimental effects of DNA lesions in genome stability,...
LA  - eng
PB  - BioMed Central (BMC)
KW  - DNA damage- ionizing radiation- cortical neurons- persistent DNA damage foci- transcription silencing- CTCF- γH2AX genomic distribution
KW  - Neurodegenerative diseases
TI  - Persistent accumulation of unrepaired DNA damage in rat cortical neurons: nuclear organization and ChIP-seq analysis of damaged DNA
TY  - journal article
ER  -