TY - JOUR AU - Kannappan, Ramaswamy AU - Matsuda, Alex AU - Ferreira-Martins, João AU - Zhang, Eric AU - Palano, Giorgia AU - Czarna, Anna AU - Cabral-Da-Silva, Mauricio Castro AU - Bastos-Carvalho, Adriana AU - Sanada, Fumihiro AU - Ide, Noriko AU - Rota, Marcello AU - Blasco , MA AU - Serrano Marugan, Manuel AU - Anversa, Piero AU - Leri, Annarosa PY - 2017 DO - 10.1016/j.ebiom.2017.01.028 SN - 23523964 UR - http://hdl.handle.net/20.500.12105/7476 AB - p53 is an important modulator of stem cell fate, but its role in cardiac progenitor cells (CPCs) is unknown. Here, we tested the effects of a single extra-copy of p53 on the function of CPCs in the presence of oxidative stress mediated by doxorubicin... LA - eng PB - Elsevier KW - DNA repair KW - Diabetes KW - Stem cell engraftment KW - Stem cell fate KW - Animals KW - Blotting, Western KW - Cell Differentiation KW - Cell Proliferation KW - Cells, Cultured KW - Diabetes Mellitus, Experimental KW - Diabetes Mellitus, Type 1 KW - Female KW - Gene Expression KW - Heart KW - Histones KW - Humans KW - Male KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Microscopy, Fluorescence KW - Myocardium KW - Myocytes, Cardiac KW - Reverse Transcriptase Polymerase Chain Reaction KW - Stem Cell Transplantation KW - Stem Cells KW - Tumor Suppressor Protein p53 TI - p53 Modulates the Fate of Cardiac Progenitor Cells Ex Vivo and in the Diabetic Heart In Vivo TY - journal article ER -