TY - JOUR AU - Perez-Garcia, Arantxa AU - Marina-Zarate, Ester AU - Alvarez-Prado, Angel Francisco AU - Ligos, Jose M. AU - Galjart, Niels AU - Ramiro, Almudena R PY - 2017 DO - 10.1038/ncomms16067 SN - 2041-1723 UR - http://hdl.handle.net/20.500.12105/5106 AB - In germinal centres (GC) mature B cells undergo intense proliferation and immunoglobulin gene modification before they differentiate into memory B cells or long-lived plasma cells (PC). GC B-cell-to-PC transition involves a major transcriptional... LA - eng PB - Nature Publishing Group KW - 3' REGULATORY REGION KW - C-MYC GENE KW - IGH LOCUS KW - T-CELLS KW - B-CELLS KW - CHROMATIN ARCHITECTURE KW - V(D)J RECOMBINATION KW - GENOME KW - EXPRESSION KW - BLIMP-1 TI - CTCF orchestrates the germinal centre transcriptional program and prevents premature plasma cell differentiation TY - journal article ER -