TY - JOUR AU - Aggarwal, Nupur AU - Koepke, Janine AU - Varela Martinez, Maria del Carmen AU - Golpon, Heiko AU - Stolk, Jan AU - Janciauskiene, Sabina AU - Koczulla, Rembert AU - Matamala, Nerea AU - Martinez-Delgado, Beatriz PY - 2016 DO - 10.1164/rccm.201510-2062LE UR - http://hdl.handle.net/20.500.12105/10601 AB - To the Editor:PiZZ (Glu342Lys) alpha-1 antitrypsin deficiency (A1ATD) is a typical genetic risk factor associated with the development of early-onset chronic obstructive pulmonary disease (COPD) with emphysema. Because A1AT is a major circulating... LA - eng PB - American Thoracic Society (ATS) KW - Aged KW - Female KW - Humans KW - Leukocytes, Mononuclear KW - Male KW - Middle Aged KW - Serine Proteases KW - alpha 1-Antitrypsin KW - alpha 1-Antitrypsin Deficiency TI - Alpha-1 Antitrypsin Regulates Transcriptional Levels of Serine Proteases in Blood Mononuclear Cells. TY - journal article ER -