TY  - JOUR
AU  - Widjaja, Ivy
AU  - Rigter, Alan
AU  - Jacobino, Shamir
AU  - van Kuppeveld, Frank J M
AU  - Leenhouts, Kees
AU  - Palomo-Sanz, Concepcion
AU  - Melero, Jose Antonio
AU  - Leusen, Jeanette H W
AU  - Haijema, Bert Jan
AU  - Rottier, Peter J M
AU  - de Haan, Cornelis A M
PY  - 2015
DO  - 10.1371/journal.pone.0130829
UR  - http://hdl.handle.net/20.500.12105/13868
AB  - The respiratory syncytial virus (RSV) fusion protein F is considered an attractive vaccine candidate especially in its prefusion conformation. We studied whether recombinant soluble RSV F proteins could be stabilized in a prefusion-like conformation...
LA  - eng
PB  - Public Library of Science (PLOS)
KW  - Antibodies, Neutralizing
KW  - Antibodies, Viral
KW  - Binding Sites
KW  - Cell Line, Tumor
KW  - Epithelial Cells
KW  - Gene Expression
KW  - HEK293 Cells
KW  - Humans
KW  - Models, Molecular
KW  - Protein Binding
KW  - Protein Multimerization
KW  - Protein Structure, Tertiary
KW  - Recombinant Proteins
KW  - Respiratory Mucosa
KW  - Respiratory Syncytial Virus, Human
KW  - Viral Fusion Proteins
TI  - Recombinant Soluble Respiratory Syncytial Virus F Protein That Lacks Heptad Repeat B, Contains a GCN4 Trimerization Motif and Is Not Cleaved Displays Prefusion-Like Characteristics
TY  - journal article
ER  -