TY  - JOUR
AU  - Fuster, Jose J.
AU  - González-Navarro, Herminia
AU  - Vinué, Angela
AU  - Molina-Sanchez, Pedro
AU  - Andres-Manzano, Maria J.
AU  - Nakayama, Keiichi I
AU  - Nakayama, Keiko
AU  - Diez-Juan, Antonio
AU  - Bernad, Antonio
AU  - Rodriguez, Cristina
AU  - Martinez-Gonzalez, Jose
AU  - Andres, Vicente
PY  - 2011
DO  - 10.1161/ATVBAHA.111.235580
SN  - 1079-5642
UR  - http://hdl.handle.net/20.500.12105/7656
AB  - OBJECTIVE: Genetic ablation of the growth suppressor p27(Kip1) (p27) in the mouse aggravates atherosclerosis coinciding with enhanced arterial cell proliferation. However, it is unknown whether molecular mechanisms that limit p27's protective function...
LA  - eng
PB  - American Heart Association (AHA)
KW  - Animals
KW  - Apolipoproteins E
KW  - Arteries
KW  - Atherosclerosis
KW  - Case-Control Studies
KW  - Cyclin-Dependent Kinase Inhibitor p27
KW  - Disease Models, Animal
KW  - Disease Progression
KW  - Female
KW  - Foam Cells
KW  - Humans
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Phosphorylation
KW  - Serine
KW  - Signal Transduction
KW  - rho GTP-Binding Proteins
KW  - rho-Associated Kinases
KW  - Cell Proliferation
TI  - Deficient p27 phosphorylation at serine 10 increases macrophage foam cell formation and aggravates atherosclerosis through a proliferation-independent mechanism
TY  - journal article
ER  -