TY - JOUR AU - Bermejo, Mercedes AU - Lopez-Huertas, Maria Rosa AU - Hedgpeth, Joe AU - Mateos, Elena AU - Rodriguez‑Mora, Sara AU - Maleno, María José AU - Plana, Montserrat AU - Swindle, John AU - Alcamí, José AU - Coiras, Mayte PY - 2015 DO - 10.1016/j.bcp.2015.02.009 SN - 0006-2952 UR - http://hdl.handle.net/20.500.12105/10298 AB - HIV-1 infection cannot be cured due to reservoirs formed early after infection. Decreasing the massive CD4+ T cell activation that occurs at the beginning of the disease would delay reservoir seeding, providing a better prognosis for patients. CD4+ T... LA - eng PB - Elsevier KW - Antiretroviral therapy KW - HIV-1 KW - Latent reservoir KW - Protein kinase C theta KW - SAMHD1 KW - Anti-HIV Agents KW - CD4-Positive T-Lymphocytes KW - Cell Membrane KW - Cell Proliferation KW - Cell Survival KW - HIV-1 KW - Humans KW - Isoenzymes KW - Jurkat Cells KW - Monomeric GTP-Binding Proteins KW - Phosphorylation KW - Protein Kinase C KW - Protein Kinase C-theta KW - Protein Transport TI - Analysis of protein kinase C theta inhibitors for the control of HIV-1 replication in human CD4+ T cells reveals an effect on retrotranscription in addition to viral transcription TY - journal article ER -