TY - JOUR AU - Cioffi, Michele AU - Trabulo, Sara M. AU - Sanchez-Ripoll, Yolanda AU - Miranda-Lorenzo, Irene AU - Lonardo, Enza AU - Dorado, Jorge AU - Reis Vieira, Catarina AU - Ramirez, Juan Carlos AU - Hidalgo, Manuel AU - Aicher, Alexandra AU - Hahn, Stephan AU - Sainz, Jr., Bruno AU - Heeschen, Christopher PY - 2015 DO - 10.1136/gutjnl-2014-308470 SN - 0017-5749 UR - http://hdl.handle.net/20.500.12105/5257 AB - Objective Cancer stem cells (CSCs) represent the root of many solid cancers including pancreatic ductal adenocarcinoma, are highly chemoresistant and represent the cellular source for disease relapse. However the mechanisms involved in these processes... LA - eng PB - BMJ Publishing Group KW - SELF-RENEWAL KW - DOWNSTREAM TARGET KW - MICRORNA CLUSTER KW - SOLID TUMORS KW - TBX3 KW - PATHWAY KW - EXPRESSION KW - TUMORIGENICITY KW - IDENTIFICATION KW - PROLIFERATION TI - The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells TY - journal article ER -