TY - JOUR AU - Rossey, Iebe AU - Gilman, Morgan S A AU - Kabeche, Stephanie C AU - Sedeyn, Koen AU - Wrapp, Daniel AU - Kanekiyo, Masaru AU - Chen, Man AU - Spitaels, Jan AU - Graham, Barney S AU - Schepens, Bert AU - McLellan, Jason S AU - Saelens, Xavier AU - Mas-Lloret, Vicente AU - Melero, Jose Antonio PY - 2017 DO - 10.1038/ncomms14158 UR - http://hdl.handle.net/20.500.12105/10416 AB - Human respiratory syncytial virus (RSV) is the main cause of lower respiratory tract infections in young children. The RSV fusion protein (F) is highly conserved and is the only viral membrane protein that is essential for infection. The prefusion... LA - eng PB - Nature Publishing Group KW - Animals KW - Antibodies, Neutralizing KW - Camelids, New World KW - Chlorocebus aethiops KW - Humans KW - Mice KW - Monocytes KW - Protein Binding KW - Respiratory Syncytial Virus Infections KW - Respiratory Syncytial Virus, Human KW - Single-Domain Antibodies KW - T-Lymphocytes KW - Vero Cells KW - Viral Fusion Proteins KW - Virus Replication TI - Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state. TY - journal article ER -