TY - GEN AU - Domínguez-Domínguez, Lourdes AU - Rava, Marta AU - Bisbal, Otilia AU - Lopez-Cortés, Luis AU - Portilla, Joaquín AU - Podzamczer, Daniel AU - Olalla, Julián AU - Fuster, Daniel AU - Rubio, Rafael AU - Jarrin Vera, Inmaculada AU - Iribarren, José Antonio AU - Moreno, Santiago AU - Cohort of the Spanish HIV/AIDS Research Network (CoRIS) PY - 2022 DO - 10.1186/s12879-022-07352-z UR - http://hdl.handle.net/20.500.12105/15136 AB - Background: To study whether the association between the CD4/CD8 ratio variation over time and the development of clinical outcomes vary in late presenters (CD4 count < 350/µL or AIDS event at enrolment) or advanced presenters (CD4 count < 200/µL or... LA - eng PB - BioMed Central (BMC) KW - Late presentation KW - CD4/CD8 KW - Clinical outcomes KW - AIDS events KW - Serious non-AIDS events KW - Mortality KW - Acquired Immunodeficiency Syndrome KW - HIV Infections KW - Adult KW - CD4 Lymphocyte Count KW - CD8-Positive T-Lymphocytes KW - Cohort Studies KW - Humans KW - Morbidity TI - Low CD4/CD8 ratio is associated with increased morbidity and mortality in late and non-late presenters: results from a multicentre cohort study, 2004-2018 TY - research article ER -