TY - GEN AU - Guerra, C AU - Navarro, P AU - Valverde, A M AU - Arribas, M AU - BrĂ¼ning, J AU - Kozak, L P AU - Kahn, C R AU - Benito, M PY - 2001 DO - 10.1172/JCI13103 SN - 0021-9738 UR - https://hdl.handle.net/20.500.12105/23090 AB - Although insulin regulates metabolism in both brown and white adipocytes, the role of these tissues in energy storage and utilization is quite different. Recombination technology using the Cre-loxP approach allows inactivation of the insulin receptor... LA - eng PB - American Society for Clinical Investigation (ASCI) KW - Adipose Tissue, Brown KW - Animals KW - Diabetes Mellitus, Type 2 KW - Female KW - Insulin KW - Insulin Resistance KW - Insulin Secretion KW - Male KW - Mice KW - Mice, Knockout KW - Mice, Transgenic KW - Phenotype KW - RNA KW - Receptor, Insulin KW - Signal Transduction KW - Tissue Distribution TI - Brown adipose tissue-specific insulin receptor knockout shows diabetic phenotype without insulin resistance. TY - research article ER -