TY - JOUR AU - Ibarra, Arkaitz AU - Schwob, Etienne AU - Mendez, Juan PY - 2008 DO - 10.1073/pnas.0803978105 UR - http://hdl.handle.net/20.500.12105/17664 AB - The six main minichromosome maintenance proteins (Mcm2-7), which presumably constitute the core of the replicative DNA helicase, are present in chromatin in large excess relative to the number of active replication forks. To evaluate the relevance of... LA - eng PB - National Academy of Sciences KW - DNA Replication KW - Replication Origin KW - Cell Proliferation KW - Chromosomal Instability KW - DNA Damage KW - HeLa Cells KW - Humans KW - S Phase KW - Transcription Factors TI - Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication. TY - journal article ER -