TY  - JOUR
AU  - Mata, Manuel
AU  - Martinez, Isidoro
AU  - Melero, Jose Antonio
AU  - Tenor, Herman
AU  - Cortijo, Julio
PY  - 2013
DO  - 10.1371/journal.pone.0069670
SN  - 1932-6203
UR  - http://hdl.handle.net/20.500.12105/6964
AB  - Respiratory syncytial virus (RSV) causes acute exacerbations in COPD and asthma. RSV infects bronchial epithelial cells (HBE) that trigger RSV associated lung pathology. This study explores whether the phosphodiesterase 4 (PDE4) inhibitor Roflumilast...
LA  - eng
PB  - Public Library of Science (PLOS)
KW  - Aminopyridines
KW  - Antioxidants
KW  - Axonemal Dyneins
KW  - Benzamides
KW  - Biomarkers
KW  - Bronchi
KW  - Cell Count
KW  - Cell Differentiation
KW  - Chloride Channels
KW  - Cilia
KW  - Cyclopropanes
KW  - Cytokines
KW  - Epithelial Cells
KW  - Forkhead Transcription Factors
KW  - Goblet Cells
KW  - Humans
KW  - Metaplasia
KW  - Mucin 5AC
KW  - Oxidative Stress
KW  - RNA, Messenger
KW  - Reactive Oxygen Species
KW  - Respiratory Syncytial Virus Infections
KW  - Respiratory Syncytial Viruses
KW  - Tubulin
KW  - Viral Load
KW  - Virus Replication
TI  - Roflumilast inhibits respiratory syncytial virus infection in human differentiated bronchial epithelial cells
TY  - journal article
ER  -