TY - JOUR AU - Di Martino, Orsola AU - Ferris, Margaret A AU - Hadwiger, Gayla AU - Sarkar, Soyi AU - Vu, Anh AU - Menendez-Gutierrez, Maria Piedad AU - Ricote, Mercedes AU - Welch, John S PY - 2022 DO - 10.3324/haematol.2021.278603 SN - 0390-6078 UR - http://hdl.handle.net/20.500.12105/13708 AB - RARA and RXRA contribute to myeloid maturation in both mice and humans, and deletion of Rxra and Rxrb augments leukemic growth in mice. While defining the domains of RXRA that are required for anti-leukemic effects in murine KMT2A-MLLT3 leukemia... LA - eng PB - Fondazione Ferrata Storti TI - RXRA DT448/9PP generates a dominant active variant capable of inducing maturation in acute myeloid leukemia cells. TY - journal article ER -