TY - GEN AU - Moreno-Gonzalez, Ines AU - Edwards III, George A. AU - Hasan, Omar AU - Gamez, Nazaret AU - Schulz, Jonathan E. AU - Fernandez-Valenzuela, Juan Jose AU - Gutierrez, Antonia AU - Soto, Claudio AU - Schulz, Paul E. PY - 2021 DO - 10.3390/diagnostics11101874 UR - http://hdl.handle.net/20.500.12105/18482 AB - Several common and debilitating neurodegenerative disorders are characterized by the intracellular accumulation of neurofibrillary tangles (NFTs), which are composed of hyperphosphorylated tau protein. In Alzheimer's disease (AD), NFTs are accompanied... LA - eng PB - Multidisciplinary Digital Publishing Institute (MDPI) KW - PET imaging KW - Tau KW - THK5351 KW - Tracer KW - Biomarker KW - Histological assessment KW - Cognitive impairment KW - Tauopathy KW - Alzheimer’s disease KW - Dementia KW - Tomografía por emisión de positrones KW - Proteínas tau KW - Trazadores radiactivos KW - Biomarcadores KW - Técnicas histológicas KW - Disfunción cognitiva KW - Tauopatías KW - Enfermedad de Alzheimer KW - Demencia KW - Mice KW - Alzheimer Disease KW - Frontotemporal Dementia KW - Gliosis KW - Neurofibrillary Tangles KW - Supranuclear Palsy, Progressive KW - tau Proteins KW - Positron-Emission Tomography KW - Positron-Emission Tomography KW - Radioactive Tracers KW - Brain Diseases TI - Longitudinal Assessment of Tau-Associated Pathology by 18F-THK5351 PET Imaging: A Histological, Biochemical, and Behavioral Study TY - research article ER -