TY - JOUR AU - Cioffi, Michele AU - Vallespinos-Serrano, Mireia AU - Trabulo, Sara M. AU - Jose Fernandez-Marcos, Pablo AU - Firment, Ashley N. AU - Vazquez, Berta N. AU - Vieira, Catarina R. AU - Mulero, Francisca AU - Camara, Juan A. AU - Cronin, Ultan P. AU - Perez, Manuel AU - Soriano, Joaquim AU - Galvez, Beatriz G. AU - Castells-Garcia, Alvaro AU - Haage, Verena AU - Raj, Deepak AU - Megias Vazquez, Diego AU - Hahn, Stephan AU - Serrano, Lourdes AU - Moon, Anne AU - Aicher, Alexandra AU - Heeschen, Christopher PY - 2015 DO - 10.1016/j.celrep.2015.08.006 SN - 2211-1247 UR - http://hdl.handle.net/20.500.12105/5390 AB - Conquering obesity has become a major socioeconomic challenge. Here, weshow that reduced expression of the miR-25-93-106b cluster, or miR-93alone, increases fat mass and, subsequently, insulin resistance.Mechanistically, we discovered an intricate... LA - eng PB - Cell Press KW - ADIPOCYTE DIFFERENTIATION KW - STEM-CELLS KW - INSULIN-RESISTANCE KW - IN-VIVO KW - TISSUE KW - IDENTIFICATION KW - REGULATOR KW - OBESITY KW - GROWTH KW - RISK TI - MiR-93 Controls Adiposity via Inhibition of Sirt7 and Tbx3 TY - journal article ER -