TY - GEN AU - de la Torre-Tarazona, Humberto Erick AU - Jiménez, R AU - Bueno, P AU - Camarero-Serrano, Sara AU - Román, L AU - Fernández-García, J L AU - Beltran, Manuela AU - Nothias, L F AU - Cachet, X AU - Paolini, J AU - Litaudon, M AU - Alcamí, José AU - Bedoya, Luis M PY - 2020 DO - 10.1016/j.bcp.2020.113937 UR - http://hdl.handle.net/20.500.12105/11339 AB - Latent HIV reservoirs are the main obstacle to eradicate HIV infection. One strategy proposes to eliminate these viral reservoirs by pharmacologically reactivating the latently infected T cells. We show here that a 4-deoxyphorbol ester derivative... LA - eng PB - Elsevier KW - HIV-1 KW - Latency reversing agents KW - Phorbol esters KW - Protein kinase C KW - Viral reactivation TI - 4-Deoxyphorbol inhibits HIV-1 infection in synergism with antiretroviral drugs and reactivates viral reservoirs through PKC/MEK activation synergizing with vorinostat TY - research article ER -