TY  - GEN
AU  - Rodero, Laura
AU  - Mellado, Emilia
AU  - Rodríguez, A Carolina
AU  - Salve, Angela
AU  - Guelfand, Liliana
AU  - Cahn, Pedro
AU  - Cuenca-Estrella, Manuel
AU  - Davel, Graciela
AU  - Rodriguez-Tudela, Juan Luis
PY  - 2003
DO  - 10.1128/aac.47.11.3653-3656.2003
SN  - 0066-4804
UR  - http://hdl.handle.net/20.500.12105/8247
AB  - Five sequential Cryptococcus neoformans isolates recovered from an AIDS patient with recurrent meningitis were analyzed. Four isolates were fluconazole susceptible, while the fifth isolate developed fluconazole resistance. Analysis of the 14-alpha...
LA  - eng
PB  - American Society for Microbiology (ASM)
KW  - Acquired Immunodeficiency Syndrome
KW  - Adult
KW  - Amino Acid Sequence
KW  - Amino Acid Substitution
KW  - Antifungal Agents
KW  - Cloning, Molecular
KW  - Cryptococcus neoformans
KW  - Cytochrome P-450 Enzyme System
KW  - Drug Resistance, Fungal
KW  - Fluconazole
KW  - Genotype
KW  - Humans
KW  - Male
KW  - Meningitis, Cryptococcal
KW  - Microbial Sensitivity Tests
KW  - Molecular Sequence Data
KW  - Oxidoreductases
KW  - Plasmids
KW  - Point Mutation
KW  - Recurrence
KW  - Sterol 14-Demethylase
TI  - G484S amino acid substitution in lanosterol 14-alpha demethylase (ERG11) is related to fluconazole resistance in a recurrent Cryptococcus neoformans clinical isolate
TY  - research article
ER  -