TY  - GEN
AU  - Hugo Villar, Victor
AU  - Vögler, Oliver
AU  - Barcelo, Francisca
AU  - Martin-Broto, Javier
AU  - Martinez-Serra, Jordi
AU  - Ruiz-Gutierrez, Valentina
AU  - Alemany, Regina
PY  - 2016
DO  - 10.1371/journal.pone.0155946
SN  - 1932-6203
UR  - http://hdl.handle.net/20.500.12105/20265
AB  - Several important biological activities have been attributed to the pentacyclic triterpene ursolic acid (UA), being its antitumoral effect extensively studied in human adenocarcinomas. In this work, we focused on the efficacy and molecular mechanisms...
LA  - eng
PB  - Public Library of Science (PLOS)
KW  - Doxorubicin
KW  - Drug Synergism
KW  - Humans
KW  - Sarcoma
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Cell Survival
KW  - Down-Regulation
KW  - Triterpenes
KW  - Apoptosis
KW  - Proto-Oncogene Proteins c-akt
KW  - Signal Transduction
KW  - Gene Expression Regulation, Neoplastic
TI  - Down-Regulation of AKT Signalling by Ursolic Acid Induces Intrinsic Apoptosis and Sensitization to Doxorubicin in Soft Tissue Sarcoma
TY  - research article
ER  -