TY  - GEN
AU  - Fernandez Agudo, Ana
AU  - Tarazona, Jose
PY  - 2025
DO  - 10.1007/s00204-025-04045-9
UR  - https://hdl.handle.net/20.500.12105/27669
AB  - New Approach Methodologies (NAMs) in Next-Generation Risk Assessment (NGRA), integrating toxicokinetics (TK) with toxicodynamics (TD), provides an accurate evaluation of combined chemical exposures. This study assesses pyrethroids, which pose...
LA  - eng
PB  - Springer Nature
KW  - New Alternative Methods (NAMs)
KW  - Next-generation risk assessment (NGRA)
KW  - Pyrethroids
KW  - Toxicodynamics
KW  - Toxicokinetics
KW  - Animals
KW  - Humans
KW  - Insecticides
KW  - No-Observed-Adverse-Effect Level
KW  - Proof of Concept Study
KW  - Pyrethrins
KW  - Risk Assessment
KW  - Toxicokinetics
TI  - A tiered next-generation risk assessment framework integrating toxicokinetics and NAM-based toxicodynamics: "proof of concept" case study using pyrethroids.
TY  - research article
ER  -