TY  - JOUR
AU  - Bueno, Maria J
AU  - Jimenez-Renard, Veronica
AU  - Samino, Sara
AU  - Capellades, Jordi
AU  - Junza, Alejandra
AU  - López-Rodríguez, María Luz
AU  - Garcia-Carceles, Javier
AU  - Lopez-Fabuel, Irene
AU  - Bolaños, Juan P
AU  - Chandel, Navdeep S
AU  - Yanes, Oscar
AU  - Colomer, Ramon
AU  - Quintela Fandino, Miguel Angel
PY  - 2019
DO  - 10.1038/s41467-019-13028-1
SN  - 2041-1723
UR  - http://hdl.handle.net/20.500.12105/9317
AB  - Upregulation of fatty acid synthase (FASN) is a common event in cancer, although its mechanistic and potential therapeutic roles are not completely understood. In this study, we establish a key role of FASN during transformation. FASN is required for...
LA  - eng
PB  - Nature Publishing Group
KW  - Animals
KW  - Cell Line
KW  - Cells, Cultured
KW  - Embryo, Mammalian
KW  - Embryonic Stem Cells
KW  - Fatty Acid Synthases
KW  - Fatty Acids
KW  - Female
KW  - Fibroblasts
KW  - HEK293 Cells
KW  - Humans
KW  - Male
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Mice, Nude
KW  - Mice, Transgenic
KW  - Neoplasms, Experimental
KW  - Tumor Burden
TI  - Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells
TY  - journal article
ER  -