TY - JOUR AU - Ruiz-Rodríguez, María Jesús AU - Oller, Jorge AU - Martínez-Martínez, Sara AU - Alarcón-Ruiz, Iván AU - Toral, Marta AU - Sun, Yilin AU - Colmenar, Ángel AU - Méndez-Olivares, María José AU - López-Maderuelo, Dolores AU - Kern, Christine B AU - Nistal, J Francisco AU - Evangelista, Arturo AU - Teixido-Tura, Gisela AU - Campanero, Miguel R AU - Redondo, Juan Miguel PY - 2024 DO - 10.1038/s44321-023-00009-7 UR - http://hdl.handle.net/20.500.12105/19365 AB - Thoracic aortic aneurysm and dissection (TAAD) is a life-threatening condition associated with Marfan syndrome (MFS), a disease caused by fibrillin-1 gene mutations. While various conditions causing TAAD exhibit aortic accumulation of the... LA - eng PB - Wiley KW - Aortic Aneurysm, Thoracic KW - Aortic Diseases KW - Aortic Dissection KW - Azides KW - Deoxyglucose KW - Marfan Syndrome KW - Animals KW - Humans KW - Mice KW - Nitric Oxide Synthase Type II KW - Proto-Oncogene Proteins c-akt KW - Versicans TI - Versican accumulation drives Nos2 induction and aortic disease in Marfan syndrome via Akt activation. TY - journal article ER -