TY - GEN AU - Santos-Barriopedro, Irene AU - Bosch-Presegué, Laia AU - Marazuela-Duque, Anna AU - de la Torre, Carolina AU - Colomer, Carlota AU - Vazquez, Berta N AU - Fuhrmann, Thomas AU - Martínez-Pastor, Bárbara AU - Lu, Wenfu AU - Braun, Thomas AU - Bober, Eva AU - Jenuwein, Thomas AU - Serrano, Lourdes AU - Esteller, Manel AU - Chen, Zhenbang AU - Barceló-Batllori, Silvia AU - Mostoslavsky, Raúl AU - Espinosa, Lluis AU - Vaquero, Alejandro PY - 2018 UR - https://hdl.handle.net/20.500.12105/26220 AB - Sirtuins are NAD-dependent deacetylases that facilitate cellular stress response. They include SirT6, which protects genome stability and regulates metabolic homeostasis through gene silencing, and whose loss induces an accelerated aging phenotype... LA - eng PB - Nature Publishing Group TI - SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway. TY - research article ER -