TY - JOUR AU - De Biasio, Alfredo AU - de Opakua, Alain Ibáñez AU - Mortuza, Gulnahar B AU - Molina, Rafael AU - Cordeiro, Tiago N AU - Castillo, Francisco AU - Villate, Maider AU - Merino, Nekane AU - Delgado, Sandra AU - Gil-Cartón, David AU - Luque, Irene AU - Diercks, Tammo AU - Bernadó, Pau AU - Montoya, Guillermo AU - Blanco, Francisco J PY - 2015 DO - 10.1038/ncomms7439 SN - 2041-1723 UR - http://hdl.handle.net/20.500.12105/10002 AB - The intrinsically disordered protein p15(PAF) regulates DNA replication and repair by binding to the proliferating cell nuclear antigen (PCNA) sliding clamp. We present the structure of the human p15(PAF)-PCNA complex. Crystallography and NMR show the... LA - eng PB - Nature Publishing Group KW - Amino Acid Motifs KW - Binding Sites KW - Carrier Proteins KW - Crystallography, X-Ray KW - DNA KW - DNA-Binding Proteins KW - Escherichia coli KW - Gene Expression KW - Humans KW - Intrinsically Disordered Proteins KW - Models, Molecular KW - Molecular Sequence Data KW - Proliferating Cell Nuclear Antigen KW - Proteasome Endopeptidase Complex KW - Protein Binding KW - Proteolysis KW - Recombinant Proteins KW - Thermodynamics KW - DNA Repair KW - DNA Replication TI - Structure of p15(PAF)-PCNA complex and implications for clamp sliding during DNA replication and repair TY - journal article ER -