TY  - GEN
AU  - Matas-Rico, Elisa
AU  - Frijlink, Elselien
AU  - van der Haar Àvila, Irene
AU  - Menegakis, Apostolos
AU  - van Zon, Maaike
AU  - Morris, Andrew J.
AU  - Koster, Jan
AU  - Salgado-Polo, Fernando
AU  - de Kivit, Sander
AU  - Lança, Telma
AU  - Mazzocca, Antonio
AU  - Johnson, Zoë
AU  - Haanen, John
AU  - Schumacher, Ton N.
AU  - Perrakis, Anastassis
AU  - Verbrugge, Inge
AU  - van den Berg, Joost H.
AU  - Borst, Jannie
AU  - Moolenaar, Wouter H.
PY  - 2021
DO  - 10.1016/j.celrep.2021.110013
UR  - http://hdl.handle.net/20.500.12105/18503
AB  - Autotaxin (ATX; ENPP2) produces lysophosphatidic acid (LPA) that regulates multiple biological functions via cognate G protein-coupled receptors LPAR1-6. ATX/LPA promotes tumor cell migration and metastasis via LPAR1 and T cell motility via LPAR2, yet...
LA  - eng
PB  - Elsevier
KW  - G protein-coupled receptors
KW  - T cells
KW  - Anti-cancer vaccination
KW  - Autotaxin
KW  - Chemorepulsion
KW  - Immunotherapy
KW  - Iysophosphatidic acid
KW  - Melanoma
KW  - Single-cell RNAseq
KW  - Tumor microenvironment
KW  - Receptores acoplados a proteínas G
KW  - Linfocitos T
KW  - Inmunoterapia
KW  - Microambiente tumoral
KW  - Neoplasias
KW  - Células
KW  - Animals
KW  - CD8-Positive T-Lymphocytes
KW  - Cell Line, Tumor
KW  - Chemotaxis
KW  - Vaccination
KW  - Humans
KW  - Lymphocytes, Tumor-Infiltrating
KW  - Lysophospholipids
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Phosphoric Diester Hydrolases
KW  - Receptors, Lysophosphatidic Acid
KW  - Tumor Microenvironment
TI  - Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T cells
TY  - research article
ER  -