TY - GEN AU - Garrido-Rodríguez, Vanesa AU - Bulnes-Ramos, Ángel AU - Olivas-Martínez, Israel AU - Pozo-Balado, María Del Mar AU - Álvarez-Ríos, Ana Isabel AU - Gutiérrez, Félix AU - Izquierdo Miguel, Rebeca AU - García, Federico AU - Tiraboschi, Juan Manuel AU - Vera-Méndez, Francisco AU - Peraire, Joaquim AU - Rull, Anna AU - Pacheco, Yolanda María AU - CoRIS Cohort PY - 2024 DO - 10.1016/j.jmii.2024.08.007 SN - 1684-1182 UR - https://hdl.handle.net/20.500.12105/26245 AB - Background: Persistence of a low CD4/CD8 ratio is associated with an increased morbimortality in people living with HIV (PLWH) under effective antiretroviral therapy. We aimed to explore the immunological significance of a persistently low CD4/CD8... LA - eng PB - Elsevier KW - CD4/CD8 ratio KW - HIV-Infection KW - Immunological dysfunction KW - Nadir-CD4 T-cell KW - sj/β-TRECs KW - Adult KW - Antiretroviral Therapy, Highly Active KW - Biomarkers KW - CD4 Lymphocyte Count KW - CD4-CD8 Ratio KW - CD4-Positive T-Lymphocytes KW - Disease Progression KW - Female KW - HIV Infections KW - Humans KW - Inflammation KW - Male KW - Middle Aged KW - Thymus Gland KW - Viral Load TI - The persistence of low CD4/CD8 ratio in chronic HIV-infection, despite ART suppression and normal CD4 levels, is associated with pre-therapy values of inflammation and thymic function. TY - research article ER -