TY - JOUR AU - Gomez-Serrano, Maria AU - Camafeita, Emilio AU - Lopez, Juan Antonio AU - Rubio, Miguel A. AU - Breton, Irene AU - Garcia-Consuegra, Ines AU - Garcia-Santos, Eva AU - Lago, Jesus AU - Sanchez-Pernaute, Andres AU - Torres, Antonio AU - Vazquez, Jesus AU - Peral, Belen PY - 2017 DO - 10.1016/j.redox.2016.12.013 SN - 2213-2317 UR - http://hdl.handle.net/20.500.12105/5125 AB - Human age-related diseases, including obesity and type 2 diabetes (T2DM), have long been associated to mitochondrial dysfunction; however, the role for adipose tissue mitochondria in these conditions remains unknown. We have tackled the impact of... LA - eng PB - Elsevier KW - Adipose tissue KW - Mitochondria KW - OXPHOS KW - Redox proteomics KW - Thiol oxidation KW - Type 2 diabetes KW - CYTOCHROME-C-OXIDASE KW - WHITE ADIPOSE-TISSUE KW - COMPLEX-I KW - INSULIN-RESISTANCE KW - QUANTITATIVE PROTEOMICS KW - TRANSCRIPTION FACTOR KW - MASS-SPECTROMETRY KW - REDOX PROTEOMICS KW - EXPRESSION KW - DISEASE TI - Differential proteomic and oxidative profiles unveil dysfunctional protein import to adipocyte mitochondria in obesity-associated aging and diabetes TY - journal article ER -